Editorials and Perspectives:

Caterina Borgna-Pignatti

The life of patients with thalassemia major
Haematologica 2010 95: 345-348. [Abstract] [Full Text] [PDF]  

Martin Jädersten

Pathophysiology and treatment of the myelodysplastic syndrome with isolated 5q deletion
Haematologica 2010 95: 348-351. [Full Text] [PDF]  

Stefania Pittaluga, Elaine S. Jaffe

T-cell/histiocyte-rich large B-cell lymphoma
Haematologica 2010 95: 352-356. [Full Text] [PDF]  

Camille Laurent, Nicolas Fazilleau, Pierre Brousset

A novel subset of T-helper cells: follicular T-helper cells and their markers
Haematologica 2010 95: 356-358. [Full Text] [PDF]  

Marvin J. Stone, Virginia Pascual

Pathophysiology of Waldenström’s macroglobulinemia
Haematologica 2010 95: 359-364. [Full Text] [PDF]  

John Koreth, Joseph H. Antin

Iron overload in hematologic malignancies and outcome of allogeneic hematopoietic stem cell transplantation
Haematologica 2010 95: 364-366. [Full Text] [PDF]  

Original Article:

Hematopoietic Cells:

Kaatje Smits, Veronica Iannucci, Veronique Stove, Peter Van Hauwe, Evelien Naessens, Pieter J. Meuwissen, Kevin K. Ariën, Mostafa Bentahir, Jean Plum, Bruno Verhasselt

Rho GTPase Cdc42 is essential for human T-cell development
Haematologica 2010 95: 367-375. [Abstract] [Full Text] [PDF]  

Thalassemia Syndromes:

Raffaella Origa, Antonio Piga, Giovanni Quarta, Gian Luca Forni, Filomena Longo, Angela Melpignano, Renzo Galanello

Pregnancy and β-thalassemia: an Italian multicenter experience
Haematologica 2010 95: 376-381. Published online November 10, 2009; doi:10.3324/haematol.2009.012393 [Abstract] [Full Text] [PDF]  

Aplastic Anemia:

Elaine M. Sloand, Matthew J. Olnes, Barbara Weinstein, Colin Wu, Jaroslaw Maciejewski, Phillip Scheinberg, Neal S. Young

Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab
Haematologica 2010 95: 382-387. [Abstract] [Full Text] [PDF] [Sloand et al. Supplementary Appendix]  

Chronic Myeloid Leukemia:

Michael Koldehoff, Lambros Kordelas, Dietrich W. Beelen, Ahmet H. Elmaagacli

Small interfering RNA against BCR-ABL transcripts sensitize mutated T315I cells to nilotinib
Haematologica 2010 95: 388-397. [Abstract] [Full Text] [PDF] [Koldehoff et al. Supplementary Appendix]  

Myelodysplastic Syndromes:

Laurent Garderet, Ladan Kobari, Christelle Mazurier, Caroline De Witte, Marie-Catherine Giarratana, Christine Pérot, Norbert Claude Gorin, Hélène Lapillonne, Luc Douay

Unimpaired terminal erythroid differentiation and preserved enucleation capacity in myelodysplastic 5q(del) clones: a single cell study
Haematologica 2010 95: 398-405. Published online October 8, 2009; doi:10.3324/haematol.2009.012773 [Abstract] [Full Text] [PDF]  

Maria Ximeri, Athanasios Galanopoulos, Mirjam Klaus, Agapi Parcharidou, Krinio Giannikou, Maria Psyllaki, Argyrios Symeonidis, Vasiliki Pappa, Zafiris Kartasis, Dimitra Liapi, Eleftheria Hatzimichael, Styliani Kokoris, Penelope Korkolopoulou, Constantina Sambani, Charalampos Pontikoglou, Helen A. Papadaki on behalf of the Hellenic MDS Study Group

Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion
Haematologica 2010 95: 406-414. Published online September 22, 2009; doi:10.3324/haematol.2009.010876 [Abstract] [Full Text] [PDF]  

Acute Myeloid Leukemia:

Nicolas Chapuis, Jérôme Tamburini, Pascale Cornillet-Lefebvre, Lucile Gillot, Valérie Bardet, Lise Willems, Sophie Park, Alexa S Green, Norbert Ifrah, François Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary

Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody
Haematologica 2010 95: 415-423. Published online December 8, 2009; doi:10.3324/haematol.2009.010785 [Abstract] [Full Text] [PDF] [Chapuis et al. Supplementary Appendix]  

Acute Promyelocytic Leukemia:

José Cervera, Pau Montesinos, Jesús M. Hernández-Rivas, María J. Calasanz, Anna Aventín, María T. Ferro, Elisa Luño, Javier Sánchez, Edo Vellenga, Chelo Rayón, Gustavo Milone, Javier de la Serna, Concha Rivas, José D. González, Mar Tormo, Elena Amutio, Marcos González, Salut Brunet, Bob Lowenberg, Miguel A. Sanz

Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy
Haematologica 2010 95: 424-431. Published online November 10, 2009; doi:10.3324/haematol.2009.013243 [Abstract] [Full Text] [PDF]  

Malignant Lymphomas:

Teresa Marafioti, Jennifer C. Paterson, Erica Ballabio, Andreas Chott, Yasodha Natkunam, Manuel Rodriguez-Justo, Anne Plonquet, Socorro M. Rodriguez-Pinilla, Wolfram Klapper, Martin-L. Hansmann, Stefano A. Pileri, Peter G. Isaacson, Harald Stein, Miguel A. Piris, David Y. Mason, Philippe Gaulard

The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation
Haematologica 2010 95: 432-439. [Abstract] [Full Text] [PDF] [Marafioti et al. Supplementary Appendix]  

Peter Van Loo, Thomas Tousseyn, Vera Vanhentenrijk, Daan Dierickx, Agnieszka Malecka, Isabelle Vanden Bempt, Gregor Verhoef, Jan Delabie, Peter Marynen, Patrick Matthys, Chris De Wolf-Peeters

T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response
Haematologica 2010 95: 440-448. Published online October 1, 2009; doi:10.3324/haematol.2009.009647 [Abstract] [Full Text] [PDF] [Van Loo et al. - Supplementary Appendix]  

Laurence Lamant, Stefano Pileri, Elena Sabattini, Laurence Brugières, Elaine S. Jaffe, Georges Delsol

Cutaneous presentation of ALK-positive anaplastic large cell lymphoma following insect bites: evidence for an association in five cases
Haematologica 2010 95: 449-455. Published online November 30, 2009; doi:10.3324/haematol.2009.015024 [Abstract] [Full Text] [PDF]  

Chronic Lymphocytic Leukemia:

Marta Segarra, Ester Lozano, Marc Corbera-Bellalta, Carme Vilardell, Maria-Teresa Cibeira, Jordi Esparza, Nora Izco, Joan Bladé, Maria C. Cid

Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways
Haematologica 2010 95: 456-463. Published online October 8, 2009; doi:10.3324/haematol.2009.006395 [Abstract] [Full Text] [PDF] [Segarra et al. Supplementary Appendix]  

Stefano Molica, Francesca R. Mauro, Vincenzo Callea, Diana Giannarelli, Francesco Lauria, Bruno Rotoli, Agostino Cortelezzi, Vincenzo Liso, Robin Foà

The utility of a prognostic index for predicting time to first treatment in early chronic lymphocytic leukemia: the GIMEMA experience
Haematologica 2010 95: 464-469. Published online November 10, 2009; doi:10.3324/haematol.2009.011767 [Abstract] [Full Text] [PDF]  

Monoclonal Gammopathies:

Zachary R. Hunter, Robert J. Manning, Christine Hanzis, Bryan T. Ciccarelli, Leukothea Ioakimidis, Christopher J. Patterson, Megan C. Lewicki, Hsuiyi Tseng, Ping Gong, Xia Liu, Yangsheng Zhou, Guang Yang, Jenny Sun, Lian Xu, Patricia Sheehy, Massimo Morra, Steven P. Treon

IgA and IgG hypogammaglobulinemia in Waldenström’s macroglobulinemia
Haematologica 2010 95: 470-475. Published online November 10, 2009; doi:10.3324/haematol.2009.010348 [Abstract] [Full Text] [PDF]  

Stem Cell Transplantation:

Emilio Paolo Alessandrino, Matteo Giovanni Della Porta, Andrea Bacigalupo, Luca Malcovati, Emanuele Angelucci, Maria Teresa Van Lint, Michele Falda, Francesco Onida, Massimo Bernardi, Stefano Guidi, Barbarella Lucarelli, Alessandro Rambaldi, Raffaella Cerretti, Paola Marenco, Pietro Pioltelli, Cristiana Pascutto, Rosi Oneto, Laura Pirolini, Renato Fanin, Alberto Bosi

Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: a GITMO study
Haematologica 2010 95: 476-484. Published online November 10, 2009; doi:10.3324/haematol.2009.011429 [Abstract] [Full Text] [PDF]  

Cell Therapy and Immunotherapy:

Marvin M. van Luijn, Martine E.D. Chamuleau, James A. Thompson, Suzanne Ostrand-Rosenberg, Theresia M. Westers, Yuri Souwer, Gert J. Ossenkoppele, S. Marieke van Ham, Arjan A. van de Loosdrecht

Class II-associated invariant chain peptide down-modulation enhances the immunogenicity of myeloid leukemic blasts resulting in increased CD4⁺ T-cell responses
Haematologica 2010 95: 485-493. Published online November 10, 2009; doi:10.3324/haematol.2009.010595 [Abstract] [Full Text] [PDF] [van Luijn et al. Supplementary Appendix]  

Decision Making and Problem Solving:

Hodgkin's Lymphoma:

Christine Herbst, Fareed A. Rehan, Corinne Brillant, Julia Bohlius, Nicole Skoetz, Holger Schulz, Ina Monsef, Lena Specht, Andreas Engert

Combined modality treatment improves tumor control and overall survival in patients with early stage Hodgkin’s lymphoma: a systematic review
Haematologica 2010 95: 494-500. Published online November 30, 2009; doi:10.3324/haematol.2009.015644 [Abstract] [Full Text] [PDF] [Herbst et al. Supplementary Appendix]  

Brief Report:

Iron Metabolism:

Guillemette Ramey, Jean-Christophe Deschemin, Béatrice Durel, François Canonne-Hergaux, Gaël Nicolas, Sophie Vaulont

Hepcidin targets ferroportin for degradation in hepatocytes
Haematologica 2010 95: 501-504. Published online September 22, 2009; doi:10.3324/haematol.2009.014399 [Abstract] [Full Text] [PDF]  

Damien R. Ashby, Daniel P. Gale, Mark Busbridge, Kevin G. Murphy, Neill D. Duncan, Tom D. Cairns, David H. Taube, Stephen R. Bloom, Frederick W.K. Tam, Richard Chapman, Patrick H. Maxwell, Peter Choi

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin
Haematologica 2010 95: 505-508. Published online October 14, 2009; doi:10.3324/haematol.2009.013136 [Abstract] [Full Text] [PDF] [Ashby et al. Supplemental Appendix]  

Malignant Lymphomas:

Katrien Van Roosbroeck, Jan Cools, Daan Dierickx, José Thomas, Peter Vandenberghe, Michel Stul, Jan Delabie, Chris De Wolf-Peeters, Peter Marynen, Iwona Wlodarska

ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions
Haematologica 2010 95: 509-513. [Abstract] [Full Text] [PDF] [Van Roosbroeck et al. Supplementary Appendix]  

Chronic Lymphocytic Leukemia:

Laurence Pearce, Liam Morgan, Thet Thet Lin, Saman Hewamana, R. James Matthews, Silvia Deaglio, Clare Rowntree, Christopher Fegan, Christopher Pepper, Paul Brennan

Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38
Haematologica 2010 95: 514-517. [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Myelodysplastic/Myeloproliferative Neoplasms:

Johanna Flach, Frank Dicker, Susanne Schnittger, Alexander Kohlmann, Torsten Haferlach, Claudia Haferlach

Mutations of JAK2 and TET2, but not CBL are detectable in a high portion of patients with refractory anemia with ring sideroblasts and thrombocytosis
Haematologica 2010 95: 518-519. Published online November 10, 2009; doi:10.3324/haematol.2009.013631 [Full Text] [PDF]  

Amyloidosis:

Mark W. Brunvand, Mitchell Bitter

Amyloidosis relapsing after autologous stem cell transplantation treated with bortezomib: normalization of detectable serum-free light chains and reversal of tissue damage with improved suitability for transplant
Haematologica 2010 95: 519-521. Published online November 10, 2009; doi:10.3324/haematol.2009.013102 [Full Text] [PDF] [Brunvald et al. Supplementary Appendix]  

Disorders of Hemostasis:

Martin Wermke, Malte von Bonin, Siegmund Gehrisch, Gabriele Siegert, Gerhard Ehninger, Uwe Platzbecker

Successful eradication of acquired factor-VIII-inhibitor using single low-dose rituximab
Haematologica 2010 95: 521-522. Published online November 10, 2009; doi:10.3324/haematol.2009.017749 [Full Text] [PDF]  

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